TOPS CAS:40567-80-4 Manufacturer Price
Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate, also known as MESNa, has a specific effect and application in biochemistry and molecular biology. It is primarily used as a reducing agent for the protection of thiol (-SH) groups in proteins and peptides.
MESNa serves as a powerful reducing agent, capable of converting disulfide bonds (-S-S-) in proteins into sulfhydryl (-SH) groups. This reduction process is essential in various scientific applications, including protein analysis, purification, and protein engineering.
Some specific applications of MESNa include:
Protein Denaturation: MESNa can be used to denature proteins by breaking disulfide bonds, thereby unfolding the protein structure and facilitating further analysis or protein purification.
Reducing Protein Aggregation: MESNa can prevent protein aggregation by reducing disulfide bonds, ensuring protein stability and solubility in solution.
Protein Labeling: MESNa can be used to introduce labels or modifications at specific cysteine residues in proteins by breaking the disulfide bonds and exposing the sulfhydryl (-SH) groups.
Protein Refolding: MESNa is used to assist protein refolding after denaturation by reducing disulfide bonds and aiding in the correct formation of protein structures.
Composition | C12H20NNaO3S |
Assay | 99% |
Appearance | White powder |
CAS No. | 40567-80-4 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |