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trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid CAS:369623-85-8

Trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid is a compound featuring a pyrrolidine ring substituted with an amino group at the 4 position and a tert-butoxycarbonyl group at the 1 position. This molecule holds significance in medicinal chemistry, particularly in the development of pharmaceuticals. Its structural complexity presents opportunities for designing novel therapeutic agents with specific pharmacological properties, potentially targeting pathways implicated in inflammatory diseases, cancer, or central nervous system disorders.


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Application and Effect:

Trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid possesses intricate structural features and holds promise in medicinal chemistry and pharmaceutical research. 1. Medicinal Chemistry: Targeted Therapy: The arrangement of functional groups in this compound suggests potential interactions with specific biological targets relevant to various diseases. It may modulate enzymatic activity, receptor binding, or other cellular processes implicated in pathological conditions, making it a promising candidate for targeted therapy development. Inflammation and Cancer: Compounds with pyrrolidine scaffolds have shown efficacy in modulating inflammatory responses and inhibiting cancer cell growth. Trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid derivatives could exhibit similar activities, making them valuable in the development of anti-inflammatory or anticancer agents. 2. Drug Development: Structure Optimization: Synthetic modifications of the pyrrolidine core and substituent groups enable structure-activity relationship (SAR) studies, facilitating the design of analogs with improved pharmacokinetic properties and enhanced target specificity. Prodrug Design: The tert-butoxycarbonyl group can serve as a prodrug moiety, facilitating drug delivery and enhancing bioavailability by protecting functional groups and improving membrane permeability. 3. Synthetic Chemistry: Diverse Synthesis Routes: The synthetic accessibility of trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid allows for the exploration of various synthetic pathways, enabling the creation of diverse libraries of analogs for biological evaluation. Convergent Synthesis: Convergent approaches can be employed to efficiently assemble complex molecular structures, streamlining the synthesis of derivatives for medicinal chemistry research. 4. Biological Evaluation: Comprehensive Studies: Derivatives of this compound undergo rigorous biological evaluation to assess their pharmacological activities, toxicity profiles, and mechanisms of action. This data guides further optimization and preclinical development towards clinical trials. In summary, trans-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid represents a promising scaffold in medicinal chemistry, offering opportunities for the development of novel therapeutic agents targeting various diseases. Its intricate structure and potential pharmacological activities make it a valuable asset in drug discovery and development efforts. Continued research and optimization are crucial to fully exploit its therapeutic potential and translate findings into clinical applications.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C10H18N2O4
Assay 99%
Appearance white powder
CAS No.  369623-85-8
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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