TRANS-DI(MU-ACETATO)BIS[O-(DI-O-TOLYLPHOSPHINO)BENZYL]DIPALLADIUM (II) CAS:172418-32-5

TRANS-DI(MU-ACETATO)BIS[O-(DI-O-TOLYLPHOSPHINO)BENZYL]DIPALLADIUM (II) has emerged as a catalyst in various organic transformations. One primary application is in cross-coupling reactions such as the Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling. In these reactions, it facilitates the formation of carbon-carbon bonds between aryl or vinyl halides and suitable coupling partners, enabling the synthesis of complex organic molecules with high efficiency. Moreover, Pd2(dba)3·CHCl3 is employed in the Mizoroki-Heck reaction, enabling the coupling of aryl halides with alkenes to form substituted alkenes. This reaction is widely utilized in the synthesis of pharmaceuticals, natural products, and materials. Additionally, TRANS-DI(MU-ACETATO)BIS[O-(DI-O-TOLYLPHOSPHINO)BENZYL]DIPALLADIUM (II) serves as a catalyst in carbon-heteroatom bond-forming reactions such as the Buchwald-Hartwig amination and the Suzuki-Miyaura coupling with amines or boronic acids, respectively. These reactions are vital in the synthesis of pharmaceuticals, agrochemicals, and materials. Furthermore, Pd2(dba)3·CHCl3 is utilized in carbonylation reactions, enabling the conversion of aryl or vinyl halides to carboxylic acids or esters. This reaction is important in the synthesis of fine chemicals and pharmaceutical intermediates. Moreover, TRANS-DI(MU-ACETATO)BIS[O-(DI-O-TOLYLPHOSPHINO)BENZYL]DIPALLADIUM (II) finds applications in asymmetric catalysis, particularly in asymmetric hydrogenation and allylic substitution reactions. Its chiral ligands confer stereocontrol, enabling the synthesis of enantioenriched compounds with high selectivity. Additionally, Pd2(dba)3·CHCl3 plays a role in carbon-carbon bond activation reactions such as the Tsuji-Trost reaction, enabling the formation of new carbon-carbon bonds through the activation of carbon-hydrogen or carbon-carbon bonds adjacent to functional groups. In summary, TRANS-DI(MU-ACETATO)BIS[O-(DI-O-TOLYLPHOSPHINO)BENZYL]DIPALLADIUM (II) is a versatile catalyst employed in a variety of cross-coupling, carbon-heteroatom bond-forming, carbonylation, asymmetric, and carbon-carbon bond activation reactions. Its applications span from the synthesis of pharmaceuticals and fine chemicals to the preparation of chiral compounds, making it a valuable tool in organic synthesis and catalysis.