Tritylolmesartanethylester CAS:144690-33-5
Tritylolmesartanethylester holds significant importance in medicinal chemistry and drug discovery, particularly in the development of angiotensin II receptor antagonists with enhanced pharmacological profiles. As a derivative of the well-known antihypertensive medication olmesartan medoxomil, this compound serves as a valuable scaffold for the synthesis and evaluation of novel analogs with improved efficacy and pharmacokinetic properties. In pharmaceutical research, Tritylolmesartanethylester is studied for its ability to modulate the renin-angiotensin system, which plays a crucial role in regulating blood pressure, fluid balance, and cardiovascular function. By investigating its interactions with angiotensin II receptors, researchers aim to design new compounds that can effectively block the physiological effects of angiotensin II, leading to the development of next-generation antihypertensive drugs with better therapeutic outcomes and reduced side effects. Furthermore, the structural modifications and pharmacological evaluations of Tritylolmesartanethylester and its analogs contribute to the understanding of structure-activity relationships (SAR) within the angiotensin receptor antagonist class. This knowledge guides the rational design of optimized drug candidates with improved receptor binding affinity, selectivity, and metabolic stability, paving the way for advancements in the treatment of cardiovascular diseases such as hypertension, heart failure, and diabetic nephropathy. Moreover, Tritylolmesartanethylester's potential applications extend to preclinical studies aimed at elucidating its pharmacokinetic and pharmacodynamic profiles, toxicity profiles, and therapeutic potential through in vitro and in vivo experiments. These investigations provide essential data for assessing its safety and efficacy, ultimately supporting its progression towards clinical trials and potential pharmaceutical development. In summary, Tritylolmesartanethylester's uses encompass its integral role in medicinal chemistry and pharmaceutical research as a platform for the design, synthesis, and evaluation of novel angiotensin II receptor antagonists, contributing to the advancement of antihypertensive therapy and cardiovascular pharmacology.
![Amino acid powder1](http://www.xindaobiotech.com/uploads/Amino-acid-powder1.jpg)
![Amino acid powder2](http://www.xindaobiotech.com/uploads/Amino-acid-powder2.jpg)
![Amino acid powder3](http://www.xindaobiotech.com/uploads/Amino-acid-powder3.jpg)
![Amino acid powder4](http://www.xindaobiotech.com/uploads/Amino-acid-powder4.jpg)
![Amino acid powder5](http://www.xindaobiotech.com/uploads/Amino-acid-powder5.jpg)
![Amino acid powder6](http://www.xindaobiotech.com/uploads/Amino-acid-powder6.jpg)
Composition | C45H44N6O3 |
Assay | 99% |
Appearance | white powder |
CAS No. | 144690-33-5 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |