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Tritylolmesartanethylester CAS:144690-33-5

Tritylolmesartanethylester is a chemical compound belonging to the class of angiotensin II receptor antagonists used in medicinal chemistry and pharmaceutical research. Its unique structure and pharmacological properties make it a subject of interest for the development of potential therapeutic agents targeting the renin-angiotensin system, particularly in the treatment of cardiovascular disorders and hypertension.


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Application and Effect:

Tritylolmesartanethylester holds significant importance in medicinal chemistry and drug discovery, particularly in the development of angiotensin II receptor antagonists with enhanced pharmacological profiles. As a derivative of the well-known antihypertensive medication olmesartan medoxomil, this compound serves as a valuable scaffold for the synthesis and evaluation of novel analogs with improved efficacy and pharmacokinetic properties. In pharmaceutical research, Tritylolmesartanethylester is studied for its ability to modulate the renin-angiotensin system, which plays a crucial role in regulating blood pressure, fluid balance, and cardiovascular function. By investigating its interactions with angiotensin II receptors, researchers aim to design new compounds that can effectively block the physiological effects of angiotensin II, leading to the development of next-generation antihypertensive drugs with better therapeutic outcomes and reduced side effects. Furthermore, the structural modifications and pharmacological evaluations of Tritylolmesartanethylester and its analogs contribute to the understanding of structure-activity relationships (SAR) within the angiotensin receptor antagonist class. This knowledge guides the rational design of optimized drug candidates with improved receptor binding affinity, selectivity, and metabolic stability, paving the way for advancements in the treatment of cardiovascular diseases such as hypertension, heart failure, and diabetic nephropathy. Moreover, Tritylolmesartanethylester's potential applications extend to preclinical studies aimed at elucidating its pharmacokinetic and pharmacodynamic profiles, toxicity profiles, and therapeutic potential through in vitro and in vivo experiments. These investigations provide essential data for assessing its safety and efficacy, ultimately supporting its progression towards clinical trials and potential pharmaceutical development. In summary, Tritylolmesartanethylester's uses encompass its integral role in medicinal chemistry and pharmaceutical research as a platform for the design, synthesis, and evaluation of novel angiotensin II receptor antagonists, contributing to the advancement of antihypertensive therapy and cardiovascular pharmacology.

Product Sample:

Amino acid powder1
Amino acid powder2

Product Packing:

Amino acid powder3
Amino acid powder4
Amino acid powder5
Amino acid powder6

Additional Information:

Composition C45H44N6O3
Assay 99%
Appearance white powder
CAS No.  144690-33-5
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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