Wortmannin CAS:19545-26-7 Manufacturer Price

Wortmannin is a naturally occurring chemical compound that is commonly used in laboratory research to study various cellular processes. It is a potent inhibitor of phosphoinositide 3-kinase (PI3K), an enzyme involved in various signaling pathways within cells.

By inhibiting PI3K, wortmannin can effectively block the activity of downstream signaling molecules and pathways that rely on PI3K. This allows researchers to investigate the roles that PI3K and its associated pathways play in processes such as cell growth, proliferation, apoptosis, intracellular trafficking, and membrane dynamics.

Wortmannin has been widely used in studies to understand the molecular mechanisms of various diseases, including cancer, inflammation, autoimmune disorders, and neurodegenerative diseases. It can help researchers identify potential therapeutic targets and develop new treatment strategies for these conditions.

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Application and Effect

Understanding cancer: PI3K signaling is often dysregulated in cancer cells, leading to uncontrolled cell growth and survival. Wortmannin has been used to study the role of PI3K in cancer development, progression, and resistance to therapy.

Investigating inflammation: PI3K signaling is also involved in the regulation of immune responses and inflammation. Wortmannin has been employed to examine the exact mechanisms by which PI3K contributes to inflammation and to identify potential targets for anti-inflammatory interventions.

Studying autophagy: Autophagy is a cellular process that involves the degradation and recycling of cellular components. PI3K signaling pathways play a critical role in regulating autophagy. Wortmannin has been used to investigate the specific contributions of PI3K in autophagy and to dissect its molecular mechanisms.

Exploring neurodegenerative diseases: PI3K signaling is implicated in several neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Wortmannin has been utilized to study the involvement of PI3K in the pathogenesis of these diseases and to identify potential therapeutic targets.

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Additional Information:

Composition	C23H24O8
Assay	99%
Appearance	White powder
CAS No.	19545-26-7
Packing	Small and bulk
Shelf Life	2 years
Storage	Store in cool and dry area
Certification	ISO.