(Z)-Methyl 2-ethoxy-3-((2′-(N’-hydroxycarbaMiMidoyl)biphenyl-4-yl)Methyl)-3H-benzo[d] iMidazole-4-carboxylate CAS:147403-65-4

The synthesis typically begins with the preparation of the benzoimidazole core through condensation reactions, followed by the coupling of the biphenylcarbamimidoyl moiety. The incorporation of the ethoxy-carbonyl group completes the synthesis, ensuring the formation of the compound with high purity suitable for biological and pharmaceutical studies. Chemical Properties and Reactivity (Z)-Methyl 2-ethoxy-3-((2'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate exhibits specific chemical properties owing to its intricate molecular structure. The benzoimidazole core contributes to its planarity and ability to engage in π-π stacking interactions, while the biphenylcarbamimidoyl and ethoxy-carbonyl functionalities influence its electronic and steric properties. These characteristics dictate its reactivity in various organic transformations and interactions with biological systems. Biological and Pharmacological Significance This compound shows potential biological activities, including antimicrobial, antiviral, and enzyme inhibitory properties. Its structural elements enable interactions with biological targets, positioning it as a candidate for therapeutic applications. By modulating specific biochemical pathways or inhibiting key enzymes, it holds promise in drug discovery and development endeavors. Applications in Medicinal Chemistry In medicinal chemistry, (Z)-Methyl 2-ethoxy-3-((2'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate serves as a scaffold for designing analogs with enhanced pharmacological properties. Structural modifications around the benzoimidazole, biphenylcarbamimidoyl, and ethoxy-carbonyl groups can optimize potency, selectivity, and pharmacokinetic profiles, aiming to develop novel therapeutic agents with improved efficacy and reduced adverse effects. Conclusion (Z)-Methyl 2-ethoxy-3-((2'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate represents a significant compound in medicinal chemistry, characterized by its complex molecular structure and potential biological activities. Its synthesis and modification pathways offer valuable insights into developing pharmaceuticals targeting various diseases. Ongoing research continues to explore its biological effects and expand its applications, underscoring its role in advancing drug discovery and development efforts.