ZEBULARINE CAS:3690-10-6

Zebularine is primarily investigated for its role as an epigenetic modulator, particularly in cancer research. By inhibiting DNA methyltransferases, zebularine can reactivate silenced genes that play crucial roles in tumor suppression and cell cycle regulation. As a result, it has shown promise in preclinical studies for treating various cancers, including solid tumors and hematological malignancies, where altered methylation patterns contribute to disease progression. In addition to its anticancer applications, zebularine is being explored for use in regenerative medicine and stem cell research. Its ability to influence DNA methylation can help guide the differentiation of stem cells, potentially leading to advancements in tissue engineering and cellular therapies. Furthermore, zebularine's capacity to modulate gene expression has implications in neurobiology, where it may be studied for its effects on neuronal function and plasticity. Overall, zebularine's unique properties make it a valuable compound in both basic and applied research, with potential applications spanning cancer therapy, regenerative medicine, and beyond. Ongoing studies are likely to reveal further insights into its mechanisms and broaden its therapeutic applicability.